The 2-Minute Rule for modafinil dosage
The 2-Minute Rule for modafinil dosage
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modafinil will reduce the extent or outcome of mavacamten by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.
This allergic reaction is usually lifetime-threatening and could potentially cause Demise. Simply call your healthcare supplier at once In case you have: a pores and skin rash, hives; fever or swollen glands that don't go away; swelling of one's face; shortness of breath; swelling on the legs; yellowing on the pores and skin or whites in the eyes; or dim urine The most common Unwanted effects of FYCOMPA include things like:
itraconazole will boost the level or effect of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Belzutifan can be a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors may possibly increase incidence or severity of adverse effects. Keep an eye on for anemia and hypoxia and reduce belzutifan dose as recommended.
When a health care provider prescribes modafinil, they offer thorough Guidance on dosages for his or her specific use.
Get crisis professional medical help When you have indications of an allergic response to Provigil: hives; issue respiratory; swelling within your facial area, lips, tongue, or throat.
mitotane decreases levels of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of. Mitotane is a strong inducer of cytochrome P-4503A4; monitor when coadministered with CYP3A4 substrates for possible dosage changes.
This drug has the likely for being abused and result in dependence; tell your Health care supplier When you've got at any time abused or been dependent on Alcoholic beverages, prescription medicines, or street prescription drugs.
Modafinil and armodafinil ended up examined as being a enhance to antipsychotic medications inside the procedure of schizophrenia. read more They showed no impact on positive indicators or cognitive overall performance.[243][244] A 2015 meta-Examination uncovered that modafinil and armodafinil may possibly slightly lessen destructive symptoms in individuals with acute schizophrenia, while they do not look valuable for individuals with the issue who are steady, with substantial damaging symptom scores.
An overdose of modafinil may lead to An array of signs or symptoms and troubles. Psychiatric symptoms may contain psychosis, mania, hallucinations, and suicidal ideation, which could happen even in people without a record of psychological ailment and will persist just after discontinuation of your drug.
Other medication may well interact with modafinil, which include prescription and in excess of-the-counter medicines, nutritional vitamins, and herbal goods. Convey to Just about every of the well being treatment suppliers about all medicines you employ now and any drugs you start or prevent making use of.
Experiences of serious dermatologic adverse effects and psychiatric functions has resulted during the FDA's Pediatric Advisory Committee unanimously recommending that a specific warning against the use of modafinil in young children be included towards the producer's labeling; use only if initially- and next-line treatments have failed and the benefits outweigh the risks.
If you are getting Provigil to treat sleepiness due to obstructive slumber apnea, you may also be handled using a ongoing beneficial airway pressure (CPAP) machine.
Stay away from or Use Alternate Drug. Avoid coadministration of delicate CYP3A4 substrates with ivosidenib or switch with substitute therapies. If coadministration is unavoidable, observe individuals for lack of therapeutic effect of those drugs.